The Mighty Mutanimals (2021 Series)

The Mighty Mutanimals is a CGI Nickelodeon cartoon series which starts as a spin-off series from Nickelodeon's Teenage Mutant Ninja Turtles. It is loosely based on an old spin-off comic with the same name.

Synopsis
Set 5 years after the series finale of TMNT 2012, the Turtles learn about huger enemies, more evil and stronger than the Shredder or the Kraang. And so, they decide to team up some allies and some former enemies to help them take down this force before it destroys them all.

The Mighty Mutanimals

 * Slash (Corey Feldman) - An immensely strong and compassionate mace-wielding mutant tortoise and the leader of the Mighty Mutanimals. He and Newtralizer have a Leo and Raph arguable relationship.
 * Leatherhead (Peter Lurie) - A fierce-looking but benign mutant alligator and the enforcer of the Mighty Mutanimals. He hopes for a peaceful future between man and mutantkind.
 * Newtralizer (Danny Trejo) - A hardcore and pugnacious mutant newt and the weapons specialist and second-in-command of the Mighty Mutanimals. Ashamed of letting his obsession with ending the Kraang menace get the best of him and ruining his partnership/friendship with Slash, he now sees how heartless he was and promises to put humans first, if it means defending the city from evil. He is often partnered up with Slash.
 * Sir Malachi (Paul Reubens) - A flamboyant and immature mutant sparrow and the mystic/diversion artist of the Mighty Mutanimals. He was formerly a human named Martin Milton, an average young geek obsessed with the roleplaying game Mazes and Mutants. While feeding the birds on his roof to get some fresh air, a canister of mutagen fell on him and mutated him into a mutant sparrow with powerful illusion casting abilities and renamed himself Sir Malachi the sparrow wizard. He has somehow gained legitimate magical powers ever since his encounter with the Turtles.
 * Dr. Tyler Rockwell/Monkey Brains (Tom Kenny) - An extremely agile and intelligent mutant chimpanzee and the acrobat, strategist and psychic of the Mighty Mutanimals. Formerly a skilled and principled neurologist working in New York, Dr. Tyler Rockwell was betrayed by his selfish and immoral collaborator Victor Falco when the latter used a sample of mutagen and some monkey DNA they were experimenting on (both of which were given by the Kraang presumably to create a new mutant minion) to mutate him into a humanoid primate with enhanced strength, agility, dexterity, and psychic abilities, which Falco sought to extract to give himself his own mind-reading powers. With a device Donnie created, he can now speak and he sounds like Gibson from the "Super Robot Monkey Team Hyper Force Go!" cartoon series. By the time the Mutanimals were formed, Monkey Brains' psychic abilities had evolved from simple emotion reading to full-on telepathy, telekinesis, and clairvoyance. Having these newfound powers, he sets up a telepathic link with his teammates which makes the use of electronic communication unnecessary (except when the Turtles have to communicate with the Mutanimals through their T-Phones).
 * Pete The Pigeon (A.J. Buckley) - A jumpy and neurotic but sweet-natured mutant pigeon and the aerial specialist of the Mighty Mutanimals. He is not as brave as his teammates, but is still a kindhearted mutant who is always willing to help others in need. He is also obsessed with bread, which acts as a source of humor for Slash and Mondo Gecko because they enjoy teasing him with it. After he joined the Mutanimals, he was given a pair of shoulder-mounted laser blasters by Donnie.
 * Mondo Gecko (Robbie Rist) - A laid-back and fearless young mutant lizard skateboarder and Candy Fine's boyfriend. He owns a rocket-powered skateboard which he uses to travel around the city and is armed with a pair of energy blades that can be connected to make a dual-ended sword.

Allies

 * The Ninja Turtles
 * Leonardo/"Leo" (Seth Green) - The leader of the Ninja Turtles who wears a blue mask and fights with two katanas. He is an avid fan of the cartoon Space Heroes.
 * Donatello/"Donnie" (Rob Paulsen) - The brains of the Ninja Turtles who wears a purple mask and fights with a bo staff that can be converted into a naginata. He has a massive crush on April O'Neil and is the one who founded the Mutanimals.
 * Raphael/"Raph" (Sean Astin) - The muscle of the Ninja Turtles who wears a red mask and fights with two sais. He is the most belligerent member of the team and is Slash's former owner.
 * "Michelangelo/"Mikey" (Greg Cipes) - The youngest of the Ninja Turtles who wears an orange mask and fights with two nunchaku which can convert into kusarigama. He has a habit for naming new mutants and is Leatherhead's first mutant friend.
 * April O'Neil (Mae Whitman) - A half-human/half-Kraang teenager. She trains Candy in the art of ninjutsu, like Splinter before her.
 * Kirby O'Neil (Keith Silverstein) - April's dad and the mutant formerly known as Kirby Bat.
 * Casey Jones (Josh Peck) - A teenage street-banging vigilante and Raphael's best friend. To better his chances at defeating his new foes, he has traded his wooden sports clubs with metal ones, gotten better rollerblades, donned a padded chest guard and arm guards for protection, been given hockey puck-shaped explosives from Mousepad, and donned a stainless steel mask given to him by April.
 * Hamato Yoshi/Splinter (Hoon Lee) - The turtles' sensei and Karai's father. Hamato Yoshi was the son and heir of the leader of the Hamato Clan, whose rivalry with the Foot Clan came to an end when he was a child. It was this victory that brought into his family Oroku Saki (Shredder), the child of the Foot Clan's leader, who Yoshi welcomed into his clan as a brother, maintaining an intense but healthy competition with him in their ninja training. As they grew older, their brotherhood was tested (and failed) when both they fell in love with the same woman, Tang Shen, who ultimately chose Yoshi over Saki. As a result, ultimately because of Saki's own jealousy and hatred, their brotherhood ended bitterly, and Yoshi and Shen married and had a daughter named Miwa. Unfortunately, when Shredder learned of his Foot Clan heritage, he attacked Yoshi in the Hamato Clan monastery, seeking to avenge his clan's extinction. During their struggle, a blow meant for Yoshi took the life of Shen, and Shredder, blaming Yoshi for his own error, burned down the monastery and left Yoshi for dead. In disgrace at the loss of both his wife and child, Yoshi left Japan to start a new life in America as "Splinter". After moving to New York City, he had just purchased the Turtles, who were four baby non-mutated red-eared sliders back then, from a pet shop when he was bumped by a strange man in the street. According to Splinter, something felt "off" about the man, so he followed him and witnessed a suspicious conversation between two human-disguised Kraangdroids, but the Kraang spotted Splinter and attacked him to keep him quiet. During the fight, the canister the Kraang were carrying broke open and splashed the Turtles and Splinter with mutagen. As the result of stepping on a brown rat while entering the alley, Splinter mutated into a humanoid mutant brown rat. Realizing he could no longer live a normal life on the surface, he retreated to the sewers where he raised his pets as his sons for fifteen years and taught them the ancient Japanese fighting art of ninjutsu. He is very protective of his sons and can sometimes be overprotective.
 * Candy Fine (Stephanie Lemelin) - Mondo's rebellious girlfriend and the "Mighty Mutanimals" incarnation of April. She was originally a Foot Clan kunoichi, but was banished due to her rebellious nature. After her banishment, she became a roller derby player, which gave her great skill on rollerblades. After accepting training from April, she was given a pair of escrima sticks for combat. She loves Mondo for who he is, and is good friends with the other Mutanimals and Jesse.
 * Jesse Kapollos/Jesse the Creeper (Dante Basco) - A determined gang-hating vigilante and Casey's childhood friend. Believed to have been killed with his family in a fire caused by the Purple Dragons when his father could not pay them protection money, Jesse actually survived and swore vengeance on the Purple Dragons, spending the next several years training himself in numerous combat styles and crafting an armored suit to strike fear into the hearts of criminals. His weapons of choice are a hockey stick, a wrist-mounted grappling hook on the left arm that can be used to swing from place to place and entangle opponents, a ton of sticky bombs, and gauntlets that can fire pepper spray and sleeping gas. He is usually partnered up with Mondo.
 * Metalhead 2.0 - A robotic turtle and the second version of Metalhead. Aside from possessing immense strength, he is equipped with rocket fists, laser eyes, rocket feet that allow flight, and numerous other features.
 * Angel (Cree Summer) - Casey's childhood friend from the ghetto. She originally worked for the Purple Dragons, but then joined the Mutanimals after she rescues them from a Purple Dragon ambush. She wields a balisong knife.
 * Jack Kurtzman (Robert Forster) - A private investigator and journalist who was investigating the disappearance of Kirby O'Neil and other missing scientists, leading to him discovering the Kraang and investigating them on his own. Displaying a book full of notes, he insists that the Kraang presence on Earth is "ancient" and actually goes back thousands of years.
 * Jacqueline Kurtzman (Bernadette Peters) - Jack Kurtzman's ex-wife. Originally a fellow journalist who fell in love with and later married Jack Kurtzman, Jacqueline eventually divorced Jack after she became fed up with his "delusional" fixation on the Kraang. While visiting her ex-husband one night to get him to sign some divorce papers so she could finalize their divorce and hook up with a rich psychiatrist named Ben Cross, she was abducted by the Kraang to use as a means to get Kurtzman to stop investigating them.
 * Detective Elissa Abernathy (Jennifer Hale) - A detective for the NYPD who knows of the Mutanimals’ existence and is never hesitant to work with them if it means protecting her city. She is also in a relationship with Kirby O’Neil.
 * Robyn O'Neil/Komodo (Nicole Sullivan) - April's aunt and Kirby's sister. A brash and impulsive detective for the NYPD, Robyn is also the partner of her brother's girlfriend, Detective Elissa Abernathy. While April admires her aunt, Kirby is regularly frustrated by his sister's overconfidence and wishes she would think before rushing into battle. Robyn's competitive nature caused for a less-than favorable first impression upon meeting the Mutanimals, especially for Newtralizer since he considered Robyn a loose cannon and a hindrance to their mission. While attempting to stop Road Hog, El Hippo, and Megamoth from stealing a vat of mutagen (which had the DNA of a komodo dragon mixed with it thanks to Megamoth), Robyn's impulsivity became her undoing when her attempt to charge at Road Hog (who had humorously bent down to pick up a lost dime) caused her to trip over the mutant pig and fall into the vat of mutagen, resulting in her transforming into a mutant komodo dragon with enhanced agility and strength, sharp claws and teeth, powerful jaw strength, and acidic saliva, and is later dubbed "Komodo" by Mondo Gecko. Though initially ashamed and bitter at her mutation, Robyn begins to enjoy her newfound mutant powers. Monkey Brains turns her back into a human in "Secrets of the Ooze".
 * Carter (Shawn Harrison) - A homeless teen living on the streets of Manhattan and a friend of the Mutanimals and Angel.
 * Doug Walker/Nostalgia Cheetah (Doug Walker/The Nostalgia Critc) - A mutant cheetah. Originally an internet reviewer named Doug Walker, this young man was captured by the Kraang and mutated into a cheetah with superhuman speed and reflexes.
 * Dr. Benson Honeycutt/Fugitoid (Peter MacNicol) - Dr. Benson Honeycutt was once a respectable and unassuming scientist working for TCRI who was developing a robot that would allow people with terminal illnesses to live longer lives by transferring their consciousness into the robot’s body. After being ordered by his superiors to weaponize the android, a suspicious Honeycutt discovered his employers were actually the Kraang, and he was mortally wounded while trying to escape them. Out of desperation, the dying Honeycutt used the untested mind-transference procedure he developed to transfer his consciousness into the android he created. After escaping from the Kraang and running into the Turtles and the Mutanimals (during which Mikey dubbed him "Fugitoid" after he lamented how he had gone from a revered member of the scientific community to a fugitive android), Donnie and Monkey Brains helped the good doctor upgrade his robotic body with telescopic limbs, laser blasters in his fingers, and numerous other features to make him a valued ally in their war against the Kraang.
 * Wildebeest Warrior (Diedrich Bader) - A brutish and burly mutant wildebeest and a former member of the Foot Clan.
 * Thrilldebeest (Steve Zahn) - A lanky and thrill-seeking mutant wildebeest and Wildebeest Warrior's brother. He seems to enjoy walking with his hands for some reason.
 * Glenn (Kenan Thompson) - A short, paunchy, African American man in his 20s and a self-proclaimed restaurateur who co-owns the Burger Bus (which he drives) with his best friend Mel. Unlike most of New York's human population, he and Mel are fond of the presence of Mutants in the city (the friendlier ones at least) and consider the Mutanimals their favorite customers and good friends.
 * Mel (Kel Mitchell) - A tall, skinny African American man in his 20s who co-owns the Burger Bus (which he cooks for) with his best friend Glenn. Unlike most of New York's human population, he and Glenn are fond of the presence of Mutants in the city (the friendlier ones at least) and consider the Mutanimals their favorite customers and good friends.
 * Rebel Triceratons
 * Traximus (Khary Payton) - A young (20 years old by human standards), strong-willed and devoted member of the Triceraton army, Traximus was well-known for his determination to stop the Kraang menace and creating his signature weapon: the gun staff. While searching New York one night to find a way to gain the upper hand against the Kraang, Traximus observed a brawl between a Kraang battalion, the Ninja Turtles and the Mutanimals and decided that the mutants would make valued allies in their war against the Kraang. After proposing this idea to his superiors, Traximus was given the task of making first contact the mutants and bringing them to Dimension Z after gaining their trust, the former which he completed by aiding the good mutants in fending off a Kraang ambush. After building a friendship with the mutants (particularly Michelangelo despite their greatly opposing personalities), Traximus escorted his new acquaintances to Dimension Z only to unwittingly lead them into an ambush where they were knocked out and captured, though Mikey managed to escape. Confronting his superiors about the ambush, Traximus was appalled to discover that they intended to brainwash the Turtles and Mutanimals into serving them instead of simply asking for allegiance as previously suggested by Traximus. While heading back to his quarters in remorse, Traximus ran into Michelangelo who, while furious at the former’s involvement with the current ordeal, understands that it was never his intention for the current situation to turn out and offers him a chance at redemption, which Traximus takes. After freeing his mutant friends and opening the portal to Earth, Traximus implored his girlfriend Alathea to leave with them to help fight the Kraang on their own, but she refuses, instead choosing to remain in Dimension Z to provide Traximus and the Mutanimals inside intel on the Triceratons’ operations. After they all return to Earth, Traximus departs, but not before being labeled an honorary Mutanimal by Slash. Being a Triceraton, Traximus possesses greatly enhanced physical attributes and is also a skilled fighter with his gunstaff, a self-made weapon of his that functions as both a melee weapon and a blaster, being able to shoot lasers, concussive blasts, plasma, electricity, and bright light.
 * Alathea (Cricket Leigh) - Seemingly the only female member of the Triceraton army, Alathea is a young yet very skilled warrior whose agility and skills with a spear make her a formidable opponent, though she is mostly favored as a scientist for the army. Stoic, apathetic, gloomy and brooding, Alathea’s indifferent nature conceals a compassionate heart and usually gives away to reveal a more playful and affectionate relationship with her boyfriend Traximus, who frequently turns to her for solace whenever he feels their conflict with the Kraang is unsolvable. In one such instance, Alathea encouraged Traximus to look outside Dimension Z on Earth for a way to gain leverage against the Kraang, which led to Traximus discovering the Ninja Turtles and the Mutanimals. She was later assigned the duty of brainwashing the mutants into being the Triceratons’ slaves, but was thwarted by Michelangelo and Traximus, who told her how corrupt their race had become in their war with the Kraang and implored her to come back to Earth with them. She declined, instead choosing to remain in Dimension Z to act as a mole for Traximus and the Mutanimals and giving them inside intel on the Triceratons’ operations.
 * Monza Ram (Jason Spisak) - The former leader of the Triceraton All-Star Team and Traximus' childhood friend.
 * Trobec (Will Friedle) - A former member of the Triceraton All-Star team.
 * Kallistrate (Michael Cornacchia) - A Triceraton mechanic.
 * Salviatore (Benjamin Diskin) - A Triceraton medic.
 * Zarra (Heather Hogan) - A Triceraton medic and Salviatore's sister.
 * Dieera (Olivia Hack) - A Triceraton merchant.
 * Miyamoto Usagi (James Sie) - A rabbit samurai swordsman who was once an ally of the Hamato Clan before mutating. His weapon is an interchangeable sword with a retractable blade and handle.
 * Ace Duck (Jeff Bennett) - A mutant duck and the pilot for the Turtle Blimp. He used to work for the Foot Clan before he joined the Mutanimals and their allies.
 * Renet (Ashley Johnson) - The current Mistress of Time, and the object of Michelangelo's amorous affections. She can control time at her will, and guards a sacred relic known as the Scepter of the Sands of Time from the Savanti sorcerers: Romero and Juliet.
 * Scale Tail (Kelly Hu) - A mutant serpent that is later revealed to be Karai, Splinter's daughter.
 * April Jones (Megan Fox) - April 20 years into the future. She's married to Casey, and is now an agent for the EPF (Earth Protection Force). She still remains an ally to the Turtles and Splinter.
 * Commander Jason Bishop (Chris Cox) - The commanding officer of the Earth Protection Force's Black Squadron. He will do anything to protect the Earth from hostile alien forces from otherworldly dimensions.
 * The League of Mutants
 * Solomon Abercrombie/King Lionheart (David Ogden Stiers) - The leader of the LOM, he was once a Shakespearean actor that got mutated by the Kraang into a lion. After the Mutanimals bust him out of a Kraang prison, he joins their cause for battle. He uses a steel-tipped sword and protects himself with his fireproof shield.
 * Lucas Maybeck/Halfcourt (Chris Rock in debut episode, Phil LaMarr in following episodes) - A mutant giraffe with a basketball player motif and an ally of the the Mutanimals. His shotgun-like air pump gun (which fires short-ranged but powerful blasts of energy at opponents by quickly pushing down on the handle) is his main weapon, along with his homemade backboard shield and a basketball that ricochets off anything it hits.
 * Sandstorm (Brian George) - An ornery mutant camel from the sands of Saudi Arabia and Halfcourt's half-cousin. His main weapon is a diamond lamp that can grant him anything he desires by rubbing it to summon his genie companion Whiskeer to aid him and his allies in times of great need. The lamp also works as a pistol that can fire laser blasts or can fire Wiskeer out as an attack. Aside from his diamond lamp, Sandstorm's other weapons include a virtually indestructible magic carpet that responds solely to his mental commands and can fly at any speed or altitude Sandstorm desires (and also be commanded to perform feats such as wrapping around an object or person, or rolling itself into a cylinder and striking like a whip or battering ram), a golden scimitar that can absorb and deflect energy attacks, and an enchanted belt-sash that can be animated by mental command to extend to any length and serve as bonds, lariat, whip or climbing rope.
 * Wiskeer (Jess Harnell) - A comical and eccentric white-furred catlike genie who lives in Sandstorm’s diamond lamp.
 * Monty Moose (Dave Thomas) - A mutant moose with a Canadian Mountie motif who joins the LOM after the Mutanimals free him from a Kraang prison. He relies on his sword and revolver.
 * Emmett Patton/Sergeant Bananas (R. Lee Erney) - A mutant gorilla. He was formerly a drill sergeant in the Vietnam War named Sergeant Emmett Patton. While leading an attack on an enemy base, Patton was separated from his platoon and stumbled upon a secret laboratory that belonged to the Triceratons. He was discovered, captured, and used as a guinea pig for the Triceratons' mutagen experiments, which mutated him into his current apelike form after he was doused with mutagen that was mixed with some gorilla DNA. Despite being held captive for years, his will would not break and he eventually escaped to seek retribution against the Triceratons. After the Mutanimals bust him out of a Kraang prison, he swears a lifetime of gratitude and joins the LOM. He relies on his brute strength and huge, hairy fists.
 * Hot Spot (Josh Keaton) - A mutant dalmatian who was once the pet of a Chinatown firefighter. During the events of the season 1 finale, Hot Spot's master was killed in an explosion while trying to evacuate a burning building while Hot Spot himself was captured by the Kraang and mutated into his current form. He joins the LOM after the Mutanimals rescue him from the Kraang prison. His main weapons are a pair of water cannons attached to his forearms that are connected to a tank he wears on his back. The cannons can project high-pressure jets of water that can be used for both offensive purposes and a means to enhance his jumps or slow his falls. He also wields a fireman's axe for close-range combat.
 * Dr. El (Jonathan Adams) - A mutant elephant and voodoo witch doctor. Originally from Africa, he got captured and later mutated by the Kraang into an elephant. He later joins the LOM after the Mutanimals rescue him from the Kraang prison. Aside from his immense strength, Doctor El is a master in the practice of black magic, his mystical expertise allowing him to perform many feats such as altering his appearance, projecting mystical bolts, casting illusions, healing injuries, controlling plants and the weather, taking control over people's minds, ect. His main weapon is a wooden staff with a skull on top of it that has jewels in the eye sockets and five feathers coming out from behind it: a red one, a blue one, a green one, a yellow one, and a white one. Whenever Doctor El wants to get rid of something or someone in a certain way, he focuses his magic into his staff, which causes one of the feathers to glow before two beams of magical energy (which are the same color as whichever feather is glowing) come out from the eye jewels and strike the target. Each colored beam has a different effect on the target (the blue beam turns the target into water and melt into a puddle, the red beam causes the target to burst into flames and crumble to ash, the green beam transforms the target into a plantlike form which makes it easier to destroy, the yellow one turns the target into light before shrinking into oblivion, and the white one transforms the target into a fragile crystalline form that shatters from any impact).
 * Russell "Russ" Gregory/Walkabout (James Patrick Stewart) - A mutant kangaroo. Originally named Russell "Russ" Gregory, he was once a dedicated game warden and professional outdoorsman who kept a vigil watch over the Australian wildlife preserve he worked at. One day, after reuniting a kangaroo joey with its family, Russell was abducted by the Kraang and unwillingly mutated into a kangaroo (since the joey's DNA was still on his person when he mutated). After doing hard time in the Kraang's mutant prison, he was freed by the Mighty Mutanimals and took on the name "Walkabout" before joining the League of Mutants. Because of his mutation, Walkabout possesses great strength in his lower body, allowing him to leap great distances and can deliver powerful kicks. He uses two boomerangs and a hunting knife.
 * Panda Khan (Lauren Tom) - A female mutant panda martial artist. Formerly an inhabitant of the Bronx Zoo, she was abducted and mutated by the Triceratons. She had the knowledge of different martial arts (namely karate, jujitsu, judo, samurai and kung fu) implanted into her mind, making her a master of hand-to-hand combat. Personality-wise, she is a kindhearted individual with a strong sense of compassion, and is often the first one to put her life on the line to protect the innocent.
 * Mousepad (Lacey Chabert) - A mutant mouse and a reserve member of the Mighty Mutanimals. She is an extremely intelligent (and slightly nerdy) young mutant (about Malachi's age) capable of creating incredible inventions and is armed with a cornucopia of self-made gadgets (which include magnetic boots, flight-enabling ankle jets, wrist blasters that fire electron beams and powerful adhesive paste, and a robot probe she can control thanks to circuitry in her helmet that can cling to her back or walk on four legs). After being mutated by the Rat King to act as a "mentee" in his quest for world domination, Mousepad was ordered to build a device that would allow her master to amplify the reach of his telepathic powers to every inch of the city. This didn't stand with the Mutanimals and they tried to stop the Rat King, only to be overwhelmed by the Squirrelanoids and be readied to die at Mousepad's hands. Out of desperation, Sir Malachi smooth talked Mousepad by complimenting her intelligence and inventions, causing the flattered mouse to develop a huge crush on him. This newfound affection, along with her uncertainty of helping her master, convinces her to rebel against the Rat King and help the Mutanimals defeat him, then to join the Mutanimals and their allies in their quest for battling the Kraang. She resides in an abandoned lab and acts as the Mutanimals' go-to-girl for technological expertise, having built Hot Spot's water cannon and the Punk Frog's weapons.
 * Wrencha (Jennifer Hale) - A rowdy yet kind female mutant koala with an Australian accent and Mousepad's partner and best friend. Similar to how Mousepad is capable of inventing extremely useful gizmos and gadgetry, Wrencha's genius lies with vehicles, as she is capable of building/upgrading any vehicle she desires, such as Newtralizer's motorcycle and the Mutanimals' battle taxi. She also has a crush on Walkabout.
 * Perri Grey (Colleen O'Shaughnessy) - An intelligent young mutant flying squirrel and Donatello's new love interest.
 * Sal (Eddie Deezen) - A jittery and neurotic mutant salamander who acts as an informant fot the Mighty Mutanimals. Though not a very strong fighter, he is able to slide through any grip on him (and through small spaces like air vents) thanks to a powerful lubricant that secretes from his body, making him virtually frictionless. In an unknown episode of Season 3, he will partner up with Mr. Weaselton.
 * Mr. Weaselton (Daran Norris) - A shady, greedy and snide mutant weasel who runs the city's underground "Kraang-fights" and acts as another informant for the Mutanimals.
 * Wingnut (Richard Steven Horvitz) - Originally an ordinary fruit bat residing in the Bronx Zoo with Panda Khan, Wingnut was abducted by the Kraang and used as a test subject for their mutagen experiments, an experience that drove him to madness. Despite his insanity, Wingnut retained a kind spirit and swore to avenge himself for what the Kraang had done to him. Befriending the mutant mosquito Screwloose, the two formed an unorthodox yet dedicated crime-fighting duo to combat the Kraang menace. He can fly, has sharp claws to fight with, and can emit sonic screams.
 * Screwloose (Max Casella) - A mutant mosquito. Originally an ordinary mosquito, he was captured by the Kraang and doused with mutagen with human DNA in it, turning him into his current state. He is a wisecracking, likeable mutant who claims to be a fearless and formidable opponent to the Kraang, but he is usually the first one to flee in the face of danger.
 * Cactus Butt (David Spade) - Originally just one of the many cacti inhabiting the vast Mojave desert in Nevada, this lifeless cactus was turned into a mutant after the Kraang detonated an experimental mutagen bomb in the desert. Even though he originates from the desert and wears biker clothing (leather jacket, white t-shirt, blue jeans, black boots, black fingerless gloves, red bandana, and black wavy hair), he is actually a comedic, funny, friendly mutant who's always ready to help his "party brothers" (Mondo and Mikey) whenever they need him.
 * Speedbeak (Freddy Rodriguez) - A mutant roadrunner and Cactus Butt's best friend. Like Cactus Butt, he was mutated by the Kraang's mutagen bomb and was transformed into an anthropomorphic state while his speed also increased tenfold.
 * Hardrock (Curtis Armstrong) - A squat, pugnacious but good-hearted and charming mutant armadillo with a passion for demolitions and explosions. Being an armadillo, he can curl up into a nigh-indestructible ball that can roll around at high speeds and ricochet off walls (like Cannonbolt from Ben 10). In combat he uses his sharp claws and numerous homemade explosives. He is dressed in black pants, black gloves, and blue goggles.
 * Claire Tashira/Scentessa (Janice Kawaye) - Claire Tashira was once a soft-spoken and insecure Asian-American teenage runaway who fled her home after constant pressure from her strict parents to do the best in school proved too much for her to bear. While resting one night in Central Park, Claire helped an injured baby skunk get back to its family, only to be sprayed by the overprotective mother skunk and ended up stumbling into a puddle of mutagen. Because some of the baby skunk's fur was still on her person when she fell, Claire was mutated into a putrid yet lovely mutant skunk with the power to generate intensely noxious fumes strong enough to render enemies unconscious, and was soon after captured by the Kraang and placed into their mutant prison (the same one from Metalhead Rewired), where she became a cellmate and close friend to the mutant armadillo Hardrock, whose poor sense of smell made him immune to her fumes. In the midst of a daring breakout carried out by the Mighty Mutanimals (who were contacted by Hardrock before he was captured), Claire lost her balance and nearly plummeted to her doom from her cell, but was saved by Hardrock. This action caused Claire to develop an attraction to the mutant armadillo which he later found out about and reciprocated. Wanting to utilize her stench without knocking her allies out cold, Claire (who was nicknamed “Scentessa” by Mondo) had Mousepad develop a special suit for her (which is basically a strapless one-piece bathing suit with a Y-shaped rubber tube that runs from the suit’s posterior to the metal gloves she wears) that allows her to project her odor from the portholes on her gloves and utilize it as concentrated blasts, smoke bombs, or means to enhance her jumps or slow her falls.
 * Mona Eliza/Mona Lisa (Emmanuelle Chirqui) - Mona Eliza was once a kind-spirited freshmen at NYU who was majoring in herpetology. While heading home one night with some samples of lizard DNA in her backpack, she was abducted by the Kraang and transformed into a mutant reptilian creature after being doused with mutagen laced with her lizard DNA samples. Her mutant form has granted her great agility, a long, sticky prehensile tongue, the ability to crawl on walls and ceilings, the power to regenerate lost limbs, and the power to camouflage into her surroundings.
 * Mrs. Jones (Rena Sofer) - Casey's long-lost mother.
 * The Punk Frogs - A tribe of mutant frog warriors who reside in the forests outside of New York.
 * Attila the Frog (Maurice LaMarche) - The stern but fair leader of the Punk Frogs. Thanks to some advice by Sir Malachi and Mousepad's genius, he gains a powerful mace as a weapon.
 * Genghis Frog (Kevin Michael Richardson) - The former general of the frog army and the most aggressive member of the Punk Frogs, though he still respects Attila's leadership. Thanks to some advice by Sir Malachi and Mousepad's genius, he gains a battle axe as a weapon.
 * Rasputin the Mad Frog (Maurice LaMarche) - Attila's advisor and right-hand frog and the resident genius of the Punk Frogs. Thanks to some advice by Sir Malachi and Mousepad's genius, he gains a bow and quiver of custom arrows as weapons.
 * Napoleon Bonafrog (Jon Heder) - The youngest member of the Punk Frogs and the current general of the frog army. Thanks to some advice by Sir Malachi and Mousepad's genius, he gains a bullwhip as a weapon.
 * Polar Bear Vikings - A group of mutant polar bears who act as a band of vikings.
 * King Iorek (Michael Dorn) - The powerful, obstinate yet caring leader of the Viking Polar Bears. He is armed with a double-bladed battle axe that can project blasts of freezing energy or fire at his opponents.
 * Prince Sven (Elijah Wood) - The brave and compassionate prince of the Viking Polar Bears. He is armed with a war hammer that can fire blasts of freezing energy.
 * Team Avatar
 * Aang (Zach Tyler Eisen) - An airbender and the Avatar, the master of all four elements.
 * Katara (Mae Whitman) - Aang's lover. A waterbender and Sokka's sister.
 * Sokka (Jack DeSena) - Katara's brother and a warrior of the Southern Water Tribe.
 * Toph (Jessie Flower) - A blind earthbender.
 * Zuko (Dante Basco) - The current heir to the Fire Nation throne and a former enemy of the Avatar.
 * Suki (Jennie Kwan) - Sokka's lover and leader of the Kyoshi Warriors.
 * Mai (Cricket Leigh) - Zuko's lover and ex-ally of Azula.
 * Ty Lee (Olivia Hack) - Mai's friend and a member of the Kyoshi Warriors.
 * Appa (Dee Bradley Baker) - Aang's loyal sky bison.
 * Momo (Dee Bradley Baker) - Aang's pet winged lemur.
 * Iroh (Greg Baldwin) - Zuko's uncle and father-figure.
 * Gladiator Raccoons
 * Marie the Raccoon (Roz Ryan) - The rotund yet beautiful leader of the Gladiator Raccoons and Pocahontas' semi-overprotective mother. Though a firm individual at first glance, she is a considerate and nurturing mutant who treats all of her subjects like family.
 * Pocahontas the Racoon (Regan Gomez) - A shy yet outgoing and flirtatious 16-year-old raccoon and Marie's daughter who has a crush on Napoleon Bonafrog. She wears a mint green bikini and fights with a spear and bolas.
 * Dove (Cathy Cavadini) - A mutant dove who has an unrequited crush on Pete.
 * Alistair Valentino/Anubis (Anthony Ruivivar) - A mutant jackal and a former treasure hunter. He wields a khopesh.
 * Penelope Valentino/Bastet (Susan Eisenberg) - A mutant cat and Anubis' sister. She wields a bullwhip.
 * Master Crik (Keone Young) - A mutant cricket and a grand master of kung fu. Originally the pet of a Shaolin monk who had immigrated to America to start up a martial arts school in Chinatown, Crik spent most of his days observing his master train in Shaolin kung-fu, which gave him a keen understanding of the martial art.
 * Mulan (Kim Mai Guest) - An attractive female mutant turtle and Master Crik's apprentice.
 * Dr. Colette Van Souci/Beautifly (Grey DeLisle) - A beautiful mutant butterfly and Monkey Brains' lover. Dr. Colette Van Souci was once a kind-natured lepidopterist (a scientist who specializes in the study of butterflies) and a colleague/lover of Tyler Rockwell. When different scientific priorities forced them to go their separate ways, Tyler and Colette were forced to end their relationship on a sad note, leaving the two of them longing to be together once more. While tending to her butterflies in her greenhouse one night, Colette was struck from above by a falling canister of mutagen which mutated her into a beautiful mutant butterfly with the ability to fly, project energy blasts from her antenna, and the power to spread a calming mist/powder that can both heal and pacify whoever inhales it. Ashamed of her new appearance, Colette spent several weeks hiding in Central Park until she was discovered by Sir Malachi and brought to the sewer lair where she was stunned yet overjoyed to be reunited with Rockwell, despite his mutation into a mutant ape.
 * Inspector Bella Paw (E.G. Daily) - A female mutant collie and Hot Spot's love interest. A brave mutant with an undying sense of loyalty, Bella was once the beloved pet of a female police officer who coincidentally was neighbors with Hot Spot’s fireman owner. Even before their mutations, Bella and Hot Spot were constantly at odds over whose master was a more valued member of society; Bella believing her owner’s job of fighting crime on a daily basis was more a more important career while Hot Spot felt his owner’s job of fighting fires and saving lives was a more significant line of duty. During the events of Showdown, Bella’s owner was killed by the Kraang when she attempted to protect a family from being captured, leaving a devastated Bella a stray on the streets and vowing to bring the Kraang to justice. Coming across a spilled canister of mutagen and drinking its contents one night, Bella was mutated into an anthropomorphic state with heightened senses of hearing and smell, as well as intelligence that allowed her to construct her personal weaponry, which consists of a gun that fires electrical bolts or vials of retro-mutagen, a police baton that can be electrified for more powerful close-range combat attacks, and an impact-absorbing riot shield. Despite her initial rivalry with Hot Spot, the two later became friends and lovers. She also tries to come off as a serious and firm individual, but delights in things dogs normally like such as fetch, being scratched behind her ears, and being tickled on her belly.
 * Street Cats
 * Pietro (Scott Menville) - A scruffy, street-smart, brave, kind-hearted and handsome young mutant alley cat with an Itallian-American accent and Felicity's love interest.
 * Benito (Collin Dean) - A young, loyal, and friendly mutant alley cat and Pietro's best friend.
 * Guiseppe (Brian Bloom) - A tough and imposing yet good-hearted mutant tabby cat and the leader of the Street Cats, as well as Pietro's father.
 * Fancy Cats
 * Felicity (Hynden Walch) - An eloquent, gentle, sweet-natured and attractive young mutant house cat and Pietro's love interest.
 * Octavia (Claudia Black) - An aristocratic and refined female mutant Parisian cat who is the leader of the Fancy Cats, as well as Felicity's mother.
 * Tiberius (Greg Ellis) - A hot-headed and aggressive mutant house cat who is Felicity's cousin and Octavia's nephew, as well as Pietro's arch-rival.
 * Seymour Foswell/Unagi (Armin Shimmerman) - A mutant electric eel. Seymour Foswell was once an overworked and irascible electircal engineer and part-time high school science teacher who held a strong resentment for powerful corporations he previously worked for which bought out small businesses and left their owners with nothing. While working late one night to fix the lights at an aquarium, Seymour was struck from above by a mutagen canister that fell through through a skylight he was standing under which shattered on him and knocked him into a tank of electric eels, causing him to mutate into an anthropomorphic electric eel with amazing electric powers.
 * Jagwar (Keith Szarabajka) - A mutant jaguar from the jungles of Central America. Initially an average jungle feline raised near the ancient Aztec temples of Central America, Jagwar's life was forever changed when the Kraang detonated an experimental mutagen bomb in his jungle home, which mutated him into an anthropomorphic state with greatly enhanced senses and physical attributes.
 * Cecil Donovan/Fang Glider (Dave Foley) - A skinny mutant flying dragon lizard and a former accountant for the Cobalt Brotherhood.
 * Mutant Warriors
 * Opossumundo (Jess Harnell) - A clever mutant opossum and the leader of the Mutant Warriors.
 * Wide Eyes (James C. Matthis III) - An eccentric mutant aye-aye lemur from the jungles of Madagascar. He possesses a high level of strength, agility, and can send victims into a trance by staring into their eyes and telling them what to do.
 * Chief Thundering Stallion/Thunderhoof (Jonathan Joss) - A strong and brave mutant bison.
 * Frillius (Greg Ellis) - A hotheaded mutant frilled lizard from the Australian outback.
 * Grasskicker (John Kassir) - A tough mutant goat.
 * Cluckette (Tress MacNeille) - A friendly mutant hen. Though not very imposing at first glance, Cluckette's sharp claws and talons do well to aid her in close-range-combat, though her main and strongest power is her ability to lay special eggs that have different effects on targets when thrown (green eggs release a highly corrosive acid on impact, yellow eggs function like flash grenades and release a blinding light to stun enemies, red eggs explode into fire like incindeary grenades, blue eggs freeze enemies in ice upon contact, orange eggs release a powerful adhesive foam that halts enemies in their tracks, purple eggs that release a "rubbery" foam that can be used as a trampoline or a means of cusioning falls, and pink eggs that work like smoke bombs and release a pink gas that can be used as a smokescreen).

Enemies

 * Mutant Master's Army
 * Mutant Master (Mark Hamill) - The self-proclaimed ultimate mutant who can turn anyone he touches into a mutant under his command and the primary antagonist of the series. He plans to turn all the people in the world into mutants so he can be the supreme mutant. He feeds off mutagen like how plants feed off sunlight.
 * Cap'n Mossback/Crabcake (Jim Cummings as Mossback, Ron Perlman as Crabcake) - A surly yet faithful mutant crab and Mutant Master's second-in-command. Originally a shrimper from New Orleans who came to New York to open his own restaurant, Cap'n Mossback's Cajun Cuisine was short-lived when a battle between the Mighty Mutanimals and the Kraang resulted in the building being reduced to rubble and Mossback swearing vengeance against the group of heroic mutants. During an attempt at ending the Mutanimals, Mossback's harpoon gun ended up breaking a tank of mutagen laced with crab DNA which poured onto him and mutated him into a large mutant crustacean with great strength, powerful crushing claws, ans a highly durable shell. Embittered by his mutation, Mossback soon met Mutant Master, who convinced the mutant crab to pledge his allegiance to him and aid him on his conquest for world domination.
 * Rufus Barnaby/Road Hog (Harland Williams) - A bumbling leather-wearing mutant pig and expert motorcyclist and the "Mighty Mutanimals" incarnation of Bebop. While a subordinate of Mutant Master, he is a rather lighthearted, humorous and optimistic mutant who genuniely believes Mutant Master is helping the world by mutating it, though he is not above helping the Mutanimals if the situation demands it. He is also a very skilled mechanic, having built his weaponized motorcycle and modifying other vehicles with weapons and whatnot. His main weapons are a crowbar and a long chain with a gutting hook attached to the end of it.
 * Santiago Delgado/El Hippo (J.B. Blanc) - A large mutant hippo and the "Mighty Mutanimals" incarnation of Rocksteady. Originally a tough and ruthless yet past-his-prime Mexican wrestler named Santiago Delgado AKA El Malevolo, he was left disgraced after a greatly damaging losing streak drove him to start taking bribes, which got him banned from entering the ring again after getting caught. Seeing Delgado in his miserable state, Road Hog appealed to the disgraced Luchador's desire to become strong again by suggesting he got himself mutated, the only price being he must swear his alliegence to Mutant Master. All too eager to get revenge on those who he felt had wronged him, Santiago doused himself with a canister of mutagen that some hippo DNA mixed into it, transforming him into a massively rotund yet immensely strong and fast mutant hippopotomas, and took on the name El Hippo after extracting revenge on his enemies.
 * Cyber Samurai (Peter Jessop) - The "Mighty Mutanimals" incarnation of Chrome Dome; an intelligent yet slinky, skinny robotic samurai created by Adrian Stockman to serve Mutant Master. He is equipped with wings for flight, laser eyes, space-age armor, rocket fists, and an energy sword.
 * Jemarcus DeCosta/Dreadmon (Dave Fennoy) - A powerful mutant wolf and the "Mighty Mutanimals" incarnation of Chris Bradford/Dogpound/Rahzar. Initially growing up penniless on the streets of Jamaica, Jemarcus DeCosta rose from the gutter over time and became the world’s most notorious jewel thief, always staying one step ahead of the law by jumping from country to country. While in New York after successfully stealing a rare diamond, Jemarcus came across a lone mutagen canister (one of the many that were lost during The Mutation Situation) inside a dumpster and took it back to his safe house, thinking it would make a good lava lamp. As he got comfortable with his pet wolf Caspian, Decosta was taken by surprise when the NYPD burst into his hideout to arrest him, which caused him to stumble and fall in alarm and spill the mutagen on himself and Caspian as he went to help his master. Because he had his bare arm slung over his wolf’s back when the mutagen came down on him, Jemarcus was transformed into a large, burly mutant wolf with superhumanly enhanced physical attributes, heightened senses, sharp claws and teeth, and the ability to disorient opponents by howling and fled into the city after furiously beating up the officers who startled him. Having sensed Jemarcus’ mutation into a wolf, Mutant Master sent Road Hog out to retrieve the mutant lupine and recruit him into the former’s army, which Dreadmon (the name given to him by Road Hog) agreed to do.
 * Trevor Marcos/Terrorcuda (Billy West) - A mutant Barracuda and the "Mighty Mutanimals" incarnation of Xever/Fishface. Having been on the wrong side of the law since his teen years, Trevor Marcos committed crimes not only for self-gain, but also for the addictive feeling of adrenaline pumping through his body whenever he evaded the police, his philosophy being: “think fast, act quicker, live in the moment”. During one such heist, Trevor attempted to evade the police by making a shortcut through the city aquarium, only to stumble and fall into the barracuda tank and be bitten by one of the barracudas before managing to escape. Unfortunately, Trevor’s luck got worse after he was struck from above by a falling mutagen canister and was mutated into a legless mutant barracuda, forcing to jump back into the barracuda tank to avoid dying from asphyxiation where he was summarily caught by the cops and given to some scientists who wished to study (and perhaps dissect) him. While en route to the scientist's laboratory, Trevor was freed from the truck that was carrying him by Road Hog, El Hippo, and Dreadmon, who then took him back to their hideout so Mutant Master could recruit him. Trevor agreed to join Mutant Master's army after he promised Trevor he could make him go fast again, which was accomplished after Adrian built Trevor a breathing harness, robotic legs with wheels for feet to allow high-speed travel by skating, and retractable blades on his arms.
 * Adrian Stockman/Megamoth (Dorian Harewood) - Baxter Stockman's cousin. He is composed, respectable, eloquent, sardonic; everything that Baxter wasn't. He accidentally gets mutated into a death's head hawk moth and obtains the powers of flight, enhanced strength, wall-crawling and sticky goo projection from his mouth to trap enemies in cocoons. While he holds no animosity towards the Mutanimals, he's lead on to believe that they were the ones who mutated his cousin, thus making him an enemy.
 * Old Hob (Steven J. Blum) - A mutant cat who acts as the commanding officer for Mutant Master's army of mutants.
 * Scorpos (Lance Henriksen) - An enemy as venomous as he is psychotic and malicious, Scorpos is a red mutant scorpion and a faithful warrior of Mutant Master's army, holding an immense lust for power and a hatred for humanity that knows no bounds. Possessing incredible strength, powerful crushing pincers and a lethal poisonous tail, Scorpos serves his master faithfully and unhesitant. He is dressed only in black pants and wristbands.
 * Mutagen Man (Roger Craig Smith) - An insane mutant blob-monster and the Turtles' ex-biggest fan. Formerly an ineffectual teenage ice-cream truck vendor who witnessed the Turtles' first battle with Baxter Stockman from his apartment window, Timothy was inspired and dedicated himself to fighting crime as a costumed vigilante calling himself "The Pulverizer" and modeled his appearance after the Turtles. Despite his good intentions, Timothy was completely inept as a crime fighter, having little to no combat skills despite Donatello's attempt to train him in basic self-defense. After being recruited into the Foot Clan (mainly to serve as a "cannon fodder") so he could gather intelligence on the Shredder's plans for the Turtles, Pulverizer volunteered to be the test subject for a supply of stolen mutagen, hoping it would turn him into a hero like the Turtles. Despite the Turtles' multiple attempts to dissuade and prevent him from mutating himself, Timothy managed to douse himself in mutagen, which caused him to mutate into a huge mutant blob of mutagen with floating organs and a disintegrating touch, a mutation that was the result of him not coming in contact with any living thing before the mutagen touched him.
 * Jack Finney/Man-Ray (Xander Berkeley) - A mutant manta ray. Originally named Jack Finney, he was once a dedicated oceanographer and environmentalist who worked hard to protect the ocean he so deeply cared for. While out on his boat late one night to rescue a manta ray from a fishing net, Jack was struck from above by a lone canister of mutagen (one of the many that were lost during the events of The Mutation Situation) and mutated into an anthropomorphic manta ray with superhuman strength, underwater breathing, powerful swimming speed, limited flight, electricity projection from his tail, and telepathic control over marine life. Deciding to use his new powers to protect the ocean, Finney took on the identity of Man-Ray, champion of the sea, and began his mission to prevent the ocean from facing ecological devastation. Over time however, Finney's determination with fulfilling his altruistic ideals caused him to lose touch with his humanity, and his efforts to stop those he felt were harming the ocean became increasingly drastic to the point where they were considered acts of eco-terrorism, which eventually put him at odds against the Mighty Mutanimals. While Man-Ray holds no animosity towards the team of heroic mutants, even coming to aid them at rare instances, he will not hesitate to fight them if he feels they are interfering with his mission, making the relationship between them difficult to understand. In battle, he wields a trident.
 * Cobalt Brotherhood
 * Boss Hugo Giovanni/Oranguton (Maurice LaMarche) - A mutant orangutan. Originally a powerful crime boss in New York's criminal underworld, Boss Hugo Giovanni realized he needed to step up his game when the city's mutant population began to make itself known to the public. Reasoning to his men that they would need to adapt to the changes in New York so as to avoid going the way of the dodo, Hugo enlisted the services of a semi-unwilling Adrian Stockman to help mutate him into a more powerful form. Using a canister of mutagen with the DNA of an orangutan mixed within it, Adrian was able to mutate Giovanni into a large, rotund, yet immensely strong and agile mutant orangutan, and was dubbed "Oranguton" by Mondo Gecko during his first encounter with the MM, which mildly annoys him since it references his weight. He wields a pair of brass knuckles and Kraang blasters in combat.
 * Cliff Douglas/Buttercup (Thomas F. Wilson) - A mutant bulldog and Giovanni's chief enforcer/second-in-command. Short on brains but big on brawns, Cliff Douglas loved being strong and thoroughly enjoyed using his strength as the chief enforcer of Boss Giovanni’s Cobalt Brotherhood. After an important gold heist that was thwarted by the Mighty Mutanimals forced the gang to retreat without so much of an ounce of the stolen gold, Cliff’s wounded dignity and desire for payback against the Mutanimals was enough for Boss Giovanni to convince him to be mutated into an even stronger form than his human one. Using some mutagen mixed with some DNA from his recently deceased pet bulldog, Cliff was mutated by Adrian Stockman into a massive mutant bulldog with immense physical strength and heightened senses of hearing and smell. Feeling as though he was missing something, Cliff had his teammate Miguel Calavera make him a spiked collar as a fashion statement, but was oblivious to the fact that Miguel had added a nametag bearing the name “Buttercup” to the collar until a re-encounter with the Mighty Mutanimals, who officically dubbed him “Buttercup”. He also wears black gym shorts.
 * Percival Blixton/Toxin (Charlie Adler) - A mutant poison dart frog and the strategist of the Cobalt Brotherhood. Uptight and irritable by nature, Percival Blixton was formerly an accountant for Boss Hugo Giovanni’s gang until he was promoted to a safecracker and strategist for the mob. Following a gold heist that was thwarted by the Mighty Mutanimals, Blixton agreed with his with Boss Giovanni that they would have to “level the playing field” if they wanted to stand up to the Mutanimals. After kidnapping Adrian Stockman and gaining an understanding of the mutagen’s workings after Boss Giovanni was transformed into a mutant orangutan, Blixton chose to be mutated into a poison dart frog, which granted him the ability to poison people through physical contact, leap great heights and distances, stick to surfaces with his sticky fingers, and fight with his prehensile, 30-foot long tongue. Unfortunately, Blixton’s mutation was considered a serious hazard to the gang by Boss Giovanni, who forced Blixton to don a suit and gloves to avoid poisoning his teammates.
 * Jacques Chevalier/Monsieur Fin (Troy Baker) - A mutant swordfish and the combat specialist of the Cobalt Brotherhood. Immigrating to America from France as a young man, professional mercenary and expert swordsman Jacques Chevalier’s skill with a blade landed him a place in Boss Hugo Giovanni’s gang as the resident combat and weapons specialist. Desiring to be mutated into something that symbolized him and his talent, Jacques was transformed into a mutant swordfish to reflect on his own love for bladed combat, though his mutation required him to wear a water-breathing device around his neck when out of water to avoid dying from asphyxiation. His main weapons are a pair of fencing swords which he wields with deadly skill.
 * Cain Westwood/Snake Eyes (Michael Rosenbaum) - A mutant rattlesnake and the marksman of the Cobalt Brotherhood. An expert at sharpshooting even as a child, Texas citizen Cain Westwood became employed as the resident marksman for Boss Giovanni’s Cobalt Brotherhood after he was dishonorably discharged from the armed forces. Following a failed gold heist (which took months of careful planning) that was thwarted by the Mighty Mutanimals, an agitated Cain agreed with his Boss that they would have to “level the playing field” and become mutants themselves to better defend themselves against the Mutanimals. Deciding to mutate himself into the same creature he first fired a gun at and killed as a boy, Cain was mutated into a mutant diamondback rattlesnake with great speed, venomous fangs, crushing coils and a flexible physiology that allows him to squeeze through small spaces and passageways (e.g. air vents) by compressing his body to certain degrees. He is also armed with metallic gauntlets that are equipped with retractable blades and wrist-mounted guns. Though an extremely dangerous opponent, Snake Eyes has a habit of taking unnecessary risks when preparing to shoot someone in order to “make things interesting”, which are usually exploited by his targets and serve as a source of frustration to his teammates.
 * Basil Carlyle/Crowhead (Lex Lang) - A mutant crow and the medic/escape artist of the Cobalt Brotherhood, as well as an avid lover of poetry. Born into a rich family of doctors that lost their fortune from having to pay for lawyers to aid them in a string of lawsuits over several failed surgical operations, Basil Carlyle sought to rebuild his family's fortune through crime, dropping out of medical school to spend years training in escapology and becoming a notorious art thief as a young man. While serving time in prison, Basil encountered Boss Giovanni and became enlisted in the Cobalt Brotherhood after managing to break Giovanni and his subordinates out from prison. Following a botched gold heist that was thwarted by the Mighty Mutanimals, Basil agreed with his cohorts that the best way to combat the heroic mutants would be to become mutants themselves. As a way of paying tribute to his favorite poet, Edgar Allan Poe, Basil decided to be mutated into a raven but was instead mutated into a crow due to Miguel Calavera putting the wrong kind of DNA into the mutagen the former exposed himself to, much to Basil's annoyance. As Crowhead, Basil possesses the power of flight and sharp claws and talons for close-range combat.
 * Miguel Calavera/Webfang (Carlos Alazraqui) - A mutant black widow and the hacker/inventor of the Cobalt Brotherhood. The son of an impoverished technical engineer who had been recruited into the Cobalt Brotherhood for his mechanical expertise, Miguel Calavera was taken under Boss Giovanni's wing following the untimely death of his father Carlos, who had been gunned down by the NYPD during a failed heist. Dropping out of college since his only source of income for tuition (his father's shares of stolen money from the Brotherhood's heists that he sent to Miguel to pay for his education) was gone, Miguel turned his talents to building devices that would aid the Brotherhood in their crimes.
 * Karuto Sagazuki (George Takei) - A mutant Japanese giant salamander and ruthless Yakuza boss.
 * Simon Bonesteel (Diedrich Bader) - The only child of a wealthy couple who made their fortune in the fashion industry by selling products made from illegally acquired animal furs, Simon Bonesteel was sent to live with his poacher uncle in Africa when the authorities began to close in on his parents' illegal activities. Growing to admire his uncle and his line of work, Simon accompanied his uncle and some friends on a hunting expedition only to be ambushed and severely injured by a lion while his guard was down. Traumatized by this ordeal, Simon made a vow to never be viewed as prey by another creature again, going on to become the world's most lethal hunter by honing his body to physical perfection and mastering in the use of several hunting weapons.
 * Dr. Phineas Manson/Dr. Mandrill (Dwight Schultz) - A mutant baboon and mad scientist, as well as a rival of Monkey Brains. Originally a military scientist who was condemned after one of his experiments went horribly awry, Dr. Phineas Manson was one of the many scientists that were abducted by the Kraang from New York City to perfect the mutagen but was later mutated into a baboon and expelled due to insubordination. Driven mad by his misfortunes, Manson decided to make his own mutants with his patented "abomination-ray" (a device fueled by mutagen that transforms whatever it fires at into a dangerous monster) to take revenge on those who wronged him.
 * Scorch (Crispin Freeman) - The third and final of Dr. Mandrill's mutant henchmen created, Scorch started out as a monitor lizard that was transformed into a muscular red-skinned wyvern-like creature with immense strength, the power of flight, and the ability to breathe fire. He is the most belligerent of Dr. Mandrill's henchmen and acts as the leader among his "brothers".
 * Buzz (Stephen Stanton) - The first of Dr. Mandrill's mutant henchmen created, Buzz was once an ordinary toad that was a test subject for Mandrill's abomination-ray, which transformed him into massive, volatile monstrosity with the power to leap great heights, generate shockwaves by slamming into the ground, withstand attacks thanks to armadillo-like plating on his back, punch holes through walls and hurt enemies with his powerful spiked tongue, and eat almost anything with his powerful jaws and teeth.
 * Spike (Thom Adcox) - The second of Dr. Mandrill's mutant henchmen created, Spike was initially an average thorny devil lizard who was zapped by Mandrill's abomination-ray, transforming him into a slender, anthropomorphic thorny devil lizard with the power to launch his spikes at high velocities, remove them for use as hand-to-hand weapons or javelins, or make them grow from anywhere on his body, allowing creation of nearly impenetrable spike armor.
 * Natalie Gates/Queen Bee (Tara Strong) - Natalie Gates was formerly a teenage melittology (beekeeping) student and a classmate and friend of Candy Fine’s who suffered constant maltreatment and mockery at the hands of her High School cheerleading captain Melissa Doyle, which caused deep damage to her already unstable emotional state and suppressed anger she had been concealing since her father left her and her mother. After a particularly cruel prank was pulled on her during her school’s homecoming dance (in which one of her own beehives was dropped on her head), Gates went off the deep end and swore revenge on those who wronged her, creating a weaponized bee-themed costume and taking to the skies as the highly vindictive and waspish vigilante named Queen Bee.
 * The Gatekeeper (Corey Burton) - A malevolent mutant owl who posessess powerful magical abilities and seeks mystical artifacts to make himself stronger and stronger. Despite his enmity with the Mutanimals, he believes Sir Malachi has potential and feels the mutant sparrow would make a worthy apprentice.
 * Claudia Birdwell/Clawcatoo (Wendie Malick) - Claudia Birdwell was once an elusive master thief with a fondness for bird-related artifacts (e.g. rare bird statues and Fabergé eggs) which she stole with the assistance of her trained pet cockatoo Victoria. While attempting to steal a rare jewel on the same night the events of The Mutation Situation occurred, a lone canister of mutagen struck Birdwell and Victoria from above, fusing them together and transforming Birdwell into a mutant sulphur-crested cockatoo with the power of flight, enhanced vision, sharp claws and talons, and the ability to harden her wing feathers and launch them at enemies as razor-sharp projectiles. While on her way home from a stakeout of a museum she was planning to rob (her target being a rare jeweled bird statue), Birdwell ran into the mutant pigeon Pete, who was immediately captivated by the mutant cockatoo and brought to the Turtles’ lair to meet the Mutanimals, where she was given the nickname “Clawcatoo” by Mondo Gecko.
 * Crew of the Orcan
 * Admiral Jelly (Robin Atkin Downes) - A mutant jellyfish and the captain of the Orcan.
 * Skewer (John DiMaggio) - A mutant lobster and the first mate of the Orcan.
 * Driftwood (Travis WIllingham) - A red-skinned mutant hammerhead shark and the bo'sun of the Orcan. He is also Seafang's cousin.
 * Squid Legs (Matt Lanter) - A mutant octopus and the quartermaster of the Orcan.
 * One-Eyed Jack (Kath Soucie) - A young mutant penguin and the navigator/look-out of the Orcan. He is also Tusker's best friend.
 * Maelstrom (David Lodge) - A mutant sea turtle and the gunner of the Orcan.
 * Blowhard (Kevin Michael Richardson) - A mutant blowfish and the master-at-arms of the Orcan.
 * Tusker (Bill Faggerbakke) - A mutant walrus and the Orcan's cabin boy.
 * Seafang (David Kaye) - A blue-skinned mutant tiger shark and the cook of the Orcan.
 * Ant Empire
 * Queen Antea (Jennifer Hale) - A mutant fire ant. The power-hungry and megalomaniacal ruler of a vast underground colony of mutant fire ants who posess superhuman strength and the ability to breathe fire. Not only desiring to take over the "upper-world" with her army, Queen Antea also wishes for a male "worthy" of her affections who can rule longside her as her queen. After obeserving the Mighty Mutanimals fighting off her soldiers, Antea develops an intense infatuation with Slash and desires to make the mutant turtle her king, even if it means killing the rest of the MM. Like the rest of her colony, Queen Antea posesses immense strength and the ability to breathe fire, and is a skilled warrior who wields her scepter (which can also project fire) with deadly skill.
 * Thoraxus (David Herman) - Queen Antea's right-hand man and advisor who is also a skilled sorcerer. The sole survivor of a colony wiped out by an exterminator, Thoraxus gained a deep resentment for humanity and was accepted into Queen Antea's colony for his mystical expertise.
 * Short Fuse (Jason Marsden) - Thoraxus' short, impulsive and irascible nephew and a disrespected member of Queen Antea's army. At first at odds with the Mighty Mutanimals, he later recognizes them as good-natured heroes and defects from the Ant Empire to aid them in their pursuit of mutant justice.
 * Savanti Romero (Ian McShane) - The former apprentice of Renet's father, he plans to obtain the Scepter of Time so he can control all time.
 * Savanti Juliet (Lauren Tom) - Savanti Romero's sister, she works with Romero to obtain the Scepter and rule all time.
 * Lou Crosby/Clown Frown (Wayne Knight) - A plump, surly and disgruntled former stand-up comic, Lou Crosby took up employment as a kid’s birthday clown after his stand-up career hit rock bottom, and even in his current job the kids he performed for didn’t find him funny. While heading home from yet another unsatisfying performance, Lou came across an ancient looking medallion and was compelled to wear it, not knowing that the medallion was cursed, and was transformed into a frightening clown-like demon as a result.
 * Purple Dragons
 * Hun (Eric Bauza) - The new leader of the Purple Dragons and a rival of Casey Jones.
 * Fong (Andrew Kishino) - A short, skinny member of the Purple Dragons and the brains of the group. He gains a three-section staff as a new weapon.
 * Sid (James Sie) - A heavily muscled member of the Purple Dragons and the enforcer of the group. He gains a sledgehammer as a new weapon.
 * Tsoi (Andrew Kishino) - A mustachioed member of the Purple Dragons and the hustler of the group. He gains a windmill shuriken as a new weapon.
 * Victor Falco/Rat King (Jeffrey Combs) - A ruler of rats and a major enemy of the Mutanimals, the Turtles and Splinter. He fell into some sewage water after his long fall and swore vengeance against Splinter and the Turtles, vowing to rule the city.
 * The Squirrelanoids - The result of an average squirrel innocently consuming the contents of a broken mutagen canister would be perhaps the most horrifying mutants yet created. Originally possessing the power of self duplication while inside a host's stomach, an encounter with the Ninja Turtles granted said squirrels a more monstrous appearance after they used Raphael as a host; the teenage terrapin's mutated blood transforming them into horrific, skeletal, red-furred abominations with immense strength, speed, agility, sharp claws, and a prehensile tongue.
 * Dream Beavers - At one point a family of simple-minded North American beavers, these unsuspecting woodland rodents were among the first creatures to be mutated by the Kraang after they arrived on Earth thousands of years ago. Deemed failures after exposure to mutagen seemingly only altered their fur color, caused different symbols to appear on their bellies and gave them the power of speech, these four beavers were used as guinea pigs for the Kraang’s trans-dimensional portal, which sent them into the “dream dimension” where they discovered they could manipulate people’s dreams and syphon off their life-force, and they proceeded to do just that for the next thousands of years. Aside from their power to change their surroundings and shape-shift while in someone's dream, the Dream Beavers can use their razor-sharp buckteeth and claws as deadly close-range weapons while their tails can be used as bludgeons.
 * Dire Beaver (Robert Englund) - A sinister purple-furred Dream Beaver and the apparent leader of the Dream Beavers. Since each of the Dream Beavers seem to represent a different type of dream, Dire represents the type of dream that expresses one's inner thoughts and desires, meaning he haunts the dreams and favors the life forces of people who have strong desires for certain things. He infiltrates Newtralizer's dream.
 * Dark Beaver (John Kassir) - A menacing red-furred Dream Beaver. Since each of the Dream Beavers seem to represent a different type of dream, Dark represents the traditional nightmare, meaning he haunts the dreams and favors the life forces of people who have strong fears and anxieties. He infiltrates Pete's dream.
 * Dread Beaver (Robert Englund) - A frightening orange-furred Dream Beaver. Since each of the Dream Beavers seem to represent a different type of dream, Dread represents the kind of dream one gets from "eating something", meaning he haunts the dreams and favors the life forces of people who have eaten bad food and are trying to sleep it off. He infiltrates Slash's dream.
 * Dave Beaver (John Kassir) - An unintelligent and cute-looking Dream Beaver. Since each of the Dream Beavers seem to represent a different type of dream, Dave represents the happy dream, meaning he "haunts" the dreams and favors the life forces of people who have happy dreams. He infiltrates Sir Malachi's dream.
 * Speed Demon (Steven J. Blum) - Formerly an ordinary muscle car, the original driver of this vehicle unknowingly drove over some mutagen left on the road, which mutated his car into a malevolent mechanical monstrosity that transforms whoever it consumes into a hideous mutant driver with an undying thirst for speed.
 * Foot Clan
 * Oroku Saki/Shredder (Kevin Michael Richardson) - The leader of the Foot Clan and Splinter's archenemy.
 * Tiger Claw (Eric Bauza) - A tall mutant bengal tiger and Shredder's second-in-command. He gains a cybernetic eye to replace his missing one, allowing him to see in infared vision.
 * Chris Bradford/Rahzar (Clancy Brown) - A skeletal mutant canine and the Shredder's star pupil. Known to the public as a world-famous martial artist, Chris Bradford was secretly a high-ranking member of the Foot Clan who used his chain of martial arts dojos to draw in and recruit new members for the ninja clan.
 * Xever/Fishface (Christian Lanz) - An unscrupulous mutant snakehead fish and the skilled criminal operative of the Foot Clan.
 * Baxter Stockman (Phil LaMarr) - An insidious and intelligent mutant housefly and mad scientist and the scientific genius of the Foot Clan.
 * Anton Zeck/Bebop (J.B. Smoove) - An eccentric mutant warthog and the master thief of the Foot Clan.
 * Ivan Steranko/Rocksteady (Fred Tatasciore) - A powerful mutant rhino and the artillery expert of the Foot Clan.
 * Shroudscale (Jeff Bennett) - A mutant chameleon and the private investigator of the Foot Clan.
 * Alopex (Sumalee Montano) - A mutant arctic fox.
 * The Kraang (Nolan North) - Aliens from Dimension X with dreams of taking over Earth. Leatherhead and Newtralizer's archenemies.
 * Kraang Prime (Roseanne Barr) - The leader of the Kraang.
 * Kraang Subprime (Gilbert Gottfried) - A spy for the Kraang that took on the appearance of April's best friend Irma Langinstein.
 * Triceratons - Alien race of anthopomorpic triceratops who are the Kraang's rivals in world domination. They originate from Dimension Z, which has an atmosphere similar to Dimension X's, but not as toxic.
 * Zanramon (Tony Todd) - The emperor of the Triceratons.
 * Commander Mozar (Kevin Grevioux) - The commander of the Triceraton army.
 * Netherdead (Peter Lurie) - Leatherhead's dark clone. Created by the Kraang.
 * The Insane Mutant Rejects
 * Bloodsucker - Their leader, a mutant leech. He doesn't speak, and communicates through telepathy, which is translated by Armaggon.
 * Armaggon (Steven J. Blum) - Second-in-command, a mutant shark from the future.
 * The Racy Vest-Wearing Monkey (Frank Welker) - A mutant gorilla. Gets very vicious when someone calls him a "racy vest-wearing monkey" (which is kind of ironic, considering that it his name).
 * Ramhorn (Fred Tatasciore) - A mutant ram. Is very agressive towards his teammates, but he still respects them.
 * Count Rattington (Tim Curry) - A mutant rat. Dressed like Alex from Stanley Kubrick's "A Clockwork Orange".
 * Insectoid (Dee Bradley Baker) - A mutant insect. His insanity is at a maximum level, making him a very dangerous enemy.
 * Groundchuck (Chuck Norris) - A mutant red bull and the more dangerous member of the rejects.
 * Dirtbag (Jeff Bennett) - A mutant mole.
 * Azula (Grey DeLisle) - Zuko's sister and the ex-heir to the Fire Nation throne.

Main Characters

 * The Mighty Mutanimals
 * Slash (Corey Feldman)
 * Leatherhead (Peter Lurie)
 * Newtralizer (Danny Trejo)
 * Dr. Tyler Rockwell/Monkey Brains (Tom Kenny)
 * Sir Malachi (Paul Reubens)
 * Pigeon Pete (A.J. Buckley)
 * Mondo Gecko (Robbie Rist)
 * Candy Fine (Stephanie Lemelin)
 * Jesse the Creeper (Dante Basco)
 * Mutant Master (Mark Hamill)
 * Cap'n Mossback/Crabcake (Jim Cummings and Ron Perlman)
 * The Kraang (Nolan North)
 * Road Hog (Harland Williams)
 * Santiago Delgado/El Hippo (J.B. Blanc)
 * Triceraton Empire
 * Zanramon (Tony Todd)
 * Commander Mozar (Kevin Grevioux)

Recurring Characters

 * The Ninja Turtles
 * Leonardo (Seth Green)
 * Raphael (Sean Astin)
 * Donatello (Rob Paulsen)
 * Michelangelo (Greg Cipes)
 * Splinter (Hoon Lee)
 * April O'Neil (Mae Whitman)
 * Kirby O'Neil (Keith Silverstein)
 * Casey Jones (Josh Peck)
 * Glenn (Kenan Thompson)
 * Mel (Kel Mitchell)
 * Robyn O'Neil (Nicole Sullivan)
 * Elissa Abernathy (Jennifer Hale)
 * Dr. Benson Honeycutt/Fugitoid (Peter MacNicol)
 * Shredder (Kevin Michael Richardson)
 * Angel (Cree Summer)
 * Wingnut (Richard Steven Horvitz)
 * Screwloose (Max Casella)
 * Miyamoto Usagi (James Sie)
 * Carter (Shawn Harrison)
 * Traximus (Khary Payton)
 * Jack Kurtzman (Robert Forster)
 * Jacqueline Kurtzman (Bernadette Peters)
 * Cyber Samurai (Peter Jessop)
 * Jemarcus DeCosta/Dreadmon (Dave Fennoy)
 * Trevor Marcos/Terrorcuda (Billy West)
 * Scorpos (Lance Henriksen)
 * Adrian Stockman/Megamoth (Dorian Harewood)
 * Punk Frogs
 * Attila the Frog (Maurice LaMarche)
 * Genghis Frog (Kevin Michael Richardson)
 * Rasputin the Mad Frog (Maurice LaMarche)
 * Napoleon Bonafrog (Jon Heder)

Supporting Characters

 * Rebel Triceratons
 * Alathea (Cricket Leigh)
 * Monza Ram (Jason Spisak)
 * Trobec (Will Friedle)
 * Kallistrate (Michael Cornacchia)
 * Salviatore (Benjamin Diskin)
 * Zarra (Heather Hogan)
 * Dieera (Olivia Hack)
 * Mutagen Man (Roger Craig Smith)
 * Ace Duck (Jeff Bennett)
 * Renet (Ashley Johnson)
 * April Jones (Megan Fox)
 * Mousepad (Lacey Chabert)
 * Wrencha (Jennifer Hale)
 * Perri Grey (Colleen O'Shaughnessy)
 * Sal (Eddie Deezen)
 * Mr. Weaselton (Daran Norris)
 * Dr. Colette Van Souci/Beautifly (Grey DeLisle)
 * Savanti Romero (Ian McShane)
 * Savanti Juliet (Lauren Tom)
 * Claudia Birdwell/Clawcatoo (Wendie Malick)
 * Dr. Mandrill (Dwight Schultz)
 * Scorch (Crispin Freeman)
 * Buzz (Stephen Stanton)
 * Spike (Thom Adcox)
 * Tiger Claw (Eric Bauza)
 * Chris Bradford/Rahzar (Clancy Brown)
 * Xever/Fishface (Christian Lanz)
 * Baxter Stockman (Phil LaMarr)
 * Anton Zeck/Bebop (J.B. Smoove)
 * Ivan Steranko/Rocksteady (Fred Tatasciore)
 * Shroudscale (Jeff Bennett)
 * Alopex (Sumalee Montano)
 * Purple Dragons
 * Hun (Eric Bauza)
 * Fong (Andrew Kishino)
 * Sid (James Sie)
 * Tsoi (Andrew Kishino)
 * Scale Tail (Kelly Hu)
 * Clown Frown (Wayne Knight)
 * Rat King (Jeffrey Combs)
 * Netherdead (Peter Lurie)
 * Speed Demon (Steven J. Blum)
 * The Insane Mutant Rejects
 * Bloodsucker
 * Armaggon (Steven J. Blum)
 * The Racy Vest-Wearing Monkey (Frank Welker)
 * Ramhorn (Fred Tatasciore)
 * Count Rattington (Tim Curry)
 * Groundchuck (Chuck Norris)
 * Dirtbag (Jeff Bennett)
 * The League of Mutants
 * King Lionheart (David Ogden Stiers)
 * Halfcourt (Chris Rock and Phil Lamarr)
 * Sandstorm (Brian George)
 * Wiskeer (Jess Harnell)
 * Monty Moose (Dave Thomas)
 * Sergeant Bananas (R. Lee Erney)
 * Hot Spot (Josh Keaton)
 * Dr. El (Jonathan Adams)
 * Walkabout (James Patrick Stewart)
 * Team Avatar
 * Aang (Zach Tyler Eisen)
 * Katara (Mae Whitman)
 * Sokka (Jack DeSena)
 * Toph (Jessie Flower)
 * Zuko (Dante Basco)
 * Suki (Jennie Kwan)
 * Mai (Cricket Leigh)
 * Ty Lee (Olivia Hack)
 * Appa (Dee Bradley Baker)
 * Momo (Dee Bradley Baker)
 * Iroh (Greg Baldwin)
 * Azula (Grey DeLisle)
 * Panda Khan (Lauren Tom)
 * Jack Finney/Man-Ray (Xander Berkeley)
 * Hardrock (Curtis Armstrong)
 * Scentessa (Janice Kawaye)
 * Dream Beavers
 * Dread Beaver (Robert Englund)
 * Dark Beaver (John Kassir)
 * Dire Beaver (Robert Englund)
 * Dave Beaver (John Kassir)
 * Alistair Valentino/Anubis (Anthony Ruivivar)
 * Penelope Valentino/Bastet (Susan Eisenberg)
 * Wildebeest Warrior (Diedrich Bader)
 * Thrilldebeest (Steve Zahn)
 * Jagwar (Keith Szarabajka)
 * Unagi (Armin Shimmerman)
 * Polar Bear Vikings
 * King Iorek (David Sobolov)
 * Prince Sven (Elijah Wood)
 * Mutant Warriors
 * Opossumundo (Jess Harnell)
 * Wide Eyes (James C. Matthis III)
 * Thunderhoof (Jonathan Joss)
 * Frillius (Greg Ellis)
 * Grasskicker
 * Cluckette (Tress MacNeille)

Confirmed Characters Yet To Appear

 * Commander Jason Bishop (Chris Cox)
 * Old Hob (Steven J. Blum)
 * Mrs. Jones (Rena Sofer)
 * Natalie Gates/Queen Bee (Tara Strong)
 * Cobalt Brotherhood
 * Boss Hugo Giovanni/Oranguton (Maurice LaMarche)
 * Buttercup (Thomas F. Wilson)
 * Toxin (Charlie Adler)
 * Jacques Chevalier/Monsieur Fin (Troy Baker)
 * Snake Eyes (Michael Rosenbaum)
 * Crowhead (Lex Lang)
 * Webfang (Carlos Alazraqui)
 * Cactus Butt (David Spade)
 * Speedbeak (Freddy Rodriguez)
 * Cecil Donovan/Fang Glider (Dave Foley)
 * Master Crik (Keone Young)
 * Mulan (Kim Mai Guest)
 * Simon Bonesteel (Diedrich Bader)
 * Mona Lisa (Emmanuelle Chirqui)
 * Doug Walker/Nostalgia Cheetah (Doug Walker/The Nostalgia Critic)
 * The Gatekeeper (Corey Burton)
 * Street Cats
 * Pietro (Scott Menville)
 * Benito (Collin Dean)
 * Giuseppe (Brian Bloom)
 * Fancy Cats
 * Felicity (Hynden Walch)
 * Octavia (Claudia Black)
 * Tiberius (Greg Ellis)
 * Crew of the Orcan
 * Admiral Jelly (Robin Atkin Downes)
 * Skewer (John DiMaggio)
 * Driftwood (Travis Willingham)
 * Squid Legs (Matt Lanter)
 * One-Eyed Jack (Kath Soucie)
 * Maelstrom (David Lodge)
 * Blowhard (Kevin Michael Richardson)
 * Tusker (Bill Faggerbakke)
 * Seafang (David Kaye)
 * Gladiator Raccoons
 * Marie the Raccoon (Roz Ryan)
 * Pocahontas the Raccoon (Regan Gomez)
 * Ant Empire
 * Queen Antea (Jennifer Hale)
 * Thoraxus (David Herman)
 * Short Fuse (Jason Marsden)

Confirmed Actors With Roles Yet To Be Confirmed

 * Dave Grohl
 * Idina Menzel
 * James Rolfe
 * Jerry Seinfeld
 * Xzibit
 * Margot Robbie
 * Nicolas Cage
 * Snoop Dogg
 * Adam Sandler
 * Arleen Sorkin
 * Alfred Molina
 * Ariel Winter
 * Nathan Vetterlein
 * Rick May
 * Dennis Bateman
 * Gary Schwartz
 * Gary Cole
 * Grant Goodeve
 * John Patrick Lowrie
 * Bumper Robinson
 * Susan Egan
 * Kelly Osbourne
 * Justine Ezarik/iJustine
 * James Hong
 * Julianne Hough
 * Sara Paxton
 * Matthew Mercer
 * Liam O'Brien
 * Gregg Berger
 * Christopher McDonald
 * Cindy Robinson
 * Gwendoline Yeo
 * Yuji Okumoto
 * Brian Tochi
 * David Kaufman
 * Derek Stephen Prince
 * David Sobolov
 * Eric Roberts
 * Jeremy Howard
 * Minae Noji
 * Nathan Kress
 * Phil Morris
 * Kevin McDonald

Crew

 * Enda MacNabola: Director, Executive Producer, Staff Writer, Creator
 * Reid007: Storyboarder, Head of Story Department, Staff Writer
 * Andrew Tighe: Voice Director, Supervising Producer, Staff Writer

Galleries

 * The Mighty Mutanimals (2018 Series)/Gallery
 * The Mighty Mutanimals (2018 Series)/Fan Art
 * The Mighty Mutanimals (2018 Series)/Concept Art

Transcripts
Main article: The Mighty Mutanimals (2018 Series)/Transcripts

Season 1

 * 1) Rise of the Mutanimals - When Donnie discovers a new mutant named Mutant Master who plans on taking over the world, the Turtles decide to take him down. But when their attempt leaves the Turtles badly injured, Donnie decides to gather some mutants together to form an alliance that will help them fight foes more stronger and powerful than them. To form this alliance, they must find Slash, Leatherhead, a reformed Newtralizer, Sir Malachi, Dr. Rockwell, Pigeon Pete, and Mondo Gecko to form the Mighty Mutanimals team.
 * 2) Beauty Divine - While patrolling the city with the Mutanimals, Mondo witnesses a beautiful girl named Candy Fine getting abducted by the Kraang. Having seen Mondo fall in love with this mysterious beauty, the other Mutanimals decide to rescue her and wonder why the Kraang would want to kidnap someone as beautiful as her.
 * 3) Miyamoto Usagi - The Mutanimals discover a hidden Kraang base and plan to destroy it. While there, Pete meets and rescues a mutant rabbit samurai named Miyamoto Usagi, who had past connections with Splinter and the Hamato Clan.
 * 4) The Return of Mutagen Man - After he is accidentally unleashed from his frozen prison, Mutagen Man goes on a rampage all throughout New York in search of April. And now, the Mutanimals must stop him before the city is destroyed!
 * 5) Labyrinth -
 * 6) Enter Shredder -
 * 7) 7 Mutant Homeboys from Dimension X - While fighting the Kraang, the Mutanimals accidentally release some insane mutants that the Kraang had planned to add to their mutant army into the city. Now, the Mutanimals and the Kraang must form a temporary truce to find and capture the insane mutants before they destroy the city!
 * 8) I Think His Name Is Adrian Stockman  - Concerned of the city's ever-growing mutant population, the New York city council commissions scientist Adrian Stockman to build a battalion of mutant-hunting androids, which prove to be a major hazard for the Mutanimals
 * 9) Of Mutants and Men</b> - The Mutanimals encounter a mutant bat and mosquito with a thirst for vengeance against the Kraang;.
 * 10) Triceratons Unite!</b> -
 * 11) Scale Tail -</b> While out on his own one night, Newtralizer encounters a mutant serpent named Scale Tail (unaware that it is Splinter's daughter Karai as a mutant) and becomes determined on bringing her down; the Turtles and Mondo Gecko try to consult Master Splinter's loss of Karai.
 * 12) Mossback and Mutants Don't Mix</b> -
 * 13) First Date</b> - Mondo decides to take Candy out to a fancy restaurant so they can officially start their relationship. Unknown to him, one of the Kraang's bases turns out to be right underneath the restaurant he's taking Candy to. And thus, the Mutanimals must head to the restaurant and warn Mondo before it is too late!
 * 14) Rat Trap</b> -
 * 15) New Vigilante in Town</b> - With reports of heavy Purple Dragon activity going around the city, the Mutanimals' schedule becomes swamped; Pete's hopes for a savior arrive in the form of Jesse the Creeper - a lowlife vigilante who has a personal grudge against the Purple Dragons.
 * 16) Wings of Love</b> -
 * 17) Return of the Punk Frogs</b> -
 * 18) Rising Mojo</b> -
 * 19) This Means War, Part 1</b> -
 * 20) This Means War, Part 2</b> -
 * 1) Return of the Punk Frogs</b> -
 * 2) Rising Mojo</b> -
 * 3) This Means War, Part 1</b> -
 * 4) This Means War, Part 2</b> -
 * 1) <b data-rte-washtml="1">This Means War, Part 1</b> -
 * 2) <b data-rte-washtml="1">This Means War, Part 2</b> -

Season 2

 * 1) <b data-rte-washtml="1">Return of the Turtles</b> - After the events of <i data-rte-washtml="1">This Means War</i>, Donnie is finally able to create an antidote for his brothers' injuries, so they can head to the surface and fight evil once again along with the Mutanimals.
 * 2) <b data-rte-washtml="1">Within the Sewers</b> - While skateboarding the sewers on Halloween night, Mondo and Candy hear an unusual noise. When Donnie links the noise to the legendary cryptid Chupacabra, Donnie, Mondo and Candy decide to hunt it down armed only with a staff (Donnie), a rocket-powered skateboard (Mondo) and a pair of escrima sticks (Candy).
 * 3) <b data-rte-washtml="1">The Citadel</b> -
 * 4) <b data-rte-washtml="1">Survival of the Fittest</b> -
 * 5) <b data-rte-washtml="1">Here's Jesse!</b> -
 * 6) <b data-rte-washtml="1">Mossback's Vendetta</b> - The Mutanimals travel to the Kraang base underwater to gather some info on the Triceratons' invasion plans; Cap'n Mossback sends Cyber Samurai to hunt down Candy and bring her to Mutant Master.
 * 7) <b data-rte-washtml="1">The Sting of Vengeance</b> -
 * 8) <b data-rte-washtml="1">Dragons Rising</b> -
 * 9) <b data-rte-washtml="1">Something's Ratty</b> - The Mutanimals learn through Splinter that the Rat King has come back and is seeking vengeance against the Mutanimals and Splinter. Now the Mutanimals must attempt to defeat the Rat King <i data-rte-washtml="1">and </i>protect Splinter at the same time!
 * 10) <b data-rte-washtml="1">The Sands of Time, Part 1</b> -
 * 11) <b data-rte-washtml="1">The Sands of Time, Part 2</b> -
 * 12) <b data-rte-washtml="1">The Pantheon</b> -
 * 13) <b data-rte-washtml="1">Netherdead</b> - The Mutanimals must rescue Leatherhead when his Kraang doppelganger Netherdead takes his place; Casey and Angel decide to help Jesse ambush the Purple Dragons.
 * 14) <b data-rte-washtml="1">Clown and Out</b> - A mutant/demon hybrid named Clown Frown is terrorizing everyone in their dream worlds, and it's up to Raph and Slash to team up and take him down before everyone's dreams are destroyed!
 * 15) <b data-rte-washtml="1">The Legend of Dark Gaia</b> -
 * 16) <b data-rte-washtml="1">Plan 12</b> - During a brawl with the Kraang at one of their bases, the Newtralizer discovers via a Communication Orb that the Kraang are intending to terraform the city with a huge laser from one of their starships. After hearing this, the Mutanimals decide they must stop it before their city is turned into a Kraang-only zone!
 * 17) <b data-rte-washtml="1">Dead or Alive</b> - The Shredder sends out Tiger Claw, Rahzar, and over 3 dozen squads of Foot Soldiers to hunt down the Mutanimals and silence them permanently. When the Turtles overhear this while out on patrol, they decide to help the Mutanimals escape into an abandoned sewer tunnel, far beyond the Foot Clan's radars.
 * 18) <b data-rte-washtml="1">Fast Forward</b> - While fighting the Kraang, the Mutanimals fall into a Time Window, sending them hurdling 20 years into the future. While trying to find a way back to their own time period, they encounter the future versions of the Turtles, Splinter, the recently-wed Casey and April Jones, and their newborn daughter Shadow.
 * 19) <b data-rte-washtml="1">Into Dimension Z!</b> -
 * 20) <b data-rte-washtml="1">The Triceraton Invasion, Part 1</b> - When the Triceratons launch a full-scale assault on New York, the Mutanimals must gather all of their allies to defeat the reptilian invaders.
 * 21) <b data-rte-washtml="1">The Triceraton Invasion, Part 2</b> -
 * 1) <b data-rte-washtml="1">Into Dimension Z!</b> -
 * 2) <b data-rte-washtml="1">The Triceraton Invasion, Part 1</b> - When the Triceratons launch a full-scale assault on New York, the Mutanimals must gather all of their allies to defeat the reptilian invaders.
 * 3) <b data-rte-washtml="1">The Triceraton Invasion, Part 2</b> -
 * 1) <b data-rte-washtml="1">The Triceraton Invasion, Part 1</b> - When the Triceratons launch a full-scale assault on New York, the Mutanimals must gather all of their allies to defeat the reptilian invaders.
 * 2) <b data-rte-washtml="1">The Triceraton Invasion, Part 2</b> -

Season 3

 * 1) <b data-rte-washtml="1">Infestation</b> - A month after the Triceratons' defeat at the hands of both the Mutanimals and the Turtles, Slash and the Newtralizer decide to investigate the wreck of a Triceraton warship after Donnie intercepts a message from one of the warship's crew members calling for help. While inside, however, they discover an alien egg that soon hatches, and now Slash and the Newtralizer must destroy the rapidly-growing alien and escape the ship before they become the alien's next victims!
 * 2) <b data-rte-washtml="1">Secrets Revealed</b> - After the Mutanimals encounter a cat named Old Hob with the intention of building a mutant army, they realize their battle with Mutant Master has not ended. Meanwhile, the Turtles return to Dimension X to search for facts surrounding Casey's lost mother.
 * 3) <b data-rte-washtml="1">The League of Mutants</b> -
 * 4) <b data-rte-washtml="1">Birth of a Rebellion</b> -
 * 5) <b data-rte-washtml="1">Into the Deep</b> - The Mutanimals face a problem when they encounter a mutant manta ray bent on protecting the ocean; the Turtles decide to take Candy with them on a mission to a Kraang base to get information for the Mutanimals.
 * 6) <b data-rte-washtml="1">Panda Khan</b> -
 * 7) <b data-rte-washtml="1">Rise of the Cobalt Brotherhood</b> -
 * 8) <b data-rte-washtml="1">Secrets of the Ooze</b> - Monkey Brains finally unlocks the secret of the mutagen and goes in search of Robyn O'Neil in hopes of mutating her back into a human;.
 * 9) <b data-rte-washtml="1">The Return of Miyamoto Usagi</b> -
 * 10) The Tides of Chaos, Part 1 -
 * 11) The Tides of Chaos, Part 2 -
 * 12) The Tides of Chaos, Part 3 -
 * 13) Planet of the Mutants -
 * 14) <b data-rte-washtml="1">Chinatown Showdown</b> -
 * 1) The Tides of Chaos, Part 3 -
 * 2) Planet of the Mutants -
 * 3) <b data-rte-washtml="1">Chinatown Showdown</b> -
 * 1) Planet of the Mutants -
 * 2) <b data-rte-washtml="1">Chinatown Showdown</b> -
 * 1) <b data-rte-washtml="1">Chinatown Showdown</b> -

Season 4

 * 1) Gladiator Raccoons Invade! -
 * 2) Return of the Dream Beavers -
 * 3) Race with the Demon II: New York Drift -
 * 4) Day of the Triceraton Revolution, Part 1 -
 * 5) Day of the Triceraton Revolution, Part 2 -
 * 1) Race with the Demon II: New York Drift -
 * 2) Day of the Triceraton Revolution, Part 1 -
 * 3) Day of the Triceraton Revolution, Part 2 -
 * 1) Day of the Triceraton Revolution, Part 1 -
 * 2) Day of the Triceraton Revolution, Part 2 -
 * 1) Day of the Triceraton Revolution, Part 1 -
 * 2) Day of the Triceraton Revolution, Part 2 -
 * 1) Day of the Triceraton Revolution, Part 2 -